Instruction Color: Research (Pilot) Data

First night of sleep overconsolidation of trauma memory

Sleep disruption – measured with wearable / apps – during first week

Harnessing IT to monitor a proxy of the behavior through digital tools that construct a digital phenotype to aid in deviations from pretraumatic behavior

Prolonged exposure intervention (Rothbaum et al, 2012). There is no consensus whether or not CBT alter the trajectory in a favourable way. We do not recommend to do this, because it could be just the waste of resourses.

Prolonged exposure in aftermath: (Rothbaum 2012, 2014).

Harnessing IT to monitor a proxy of the behavior through digital tools that construct a digital phenotype to aid in deviations from pretraumatic behavior

Propranolol (Pitman et al., 2006). In five studies the initial positive study was not supported, the meta-analysis does not support its use (Argolo et al, 2015).

Low cgnitive flexibility (Ben-Zion et al, 2018).

Harnessing IT to monitor a proxy of the behavior through digital tools that construct a digital phenotype to aid in deviations from pretraumatic behavior

Hydrocortisone intervention (100-140 mg, intravenous, single bolus); it is much more effective if given at night (Zohar et al, 2011). (Weis et al, 2006, Delahanty et al, 2013).