First night of sleep overconsolidation of trauma memory
Sleep disruption – measured with wearable / apps – during first week
Harnessing IT to monitor a proxy of the behavior through digital tools that construct a digital phenotype to aid in deviations from pretraumatic behavior and early interventions
SSRI as a secondary prevention (duration 3-4 month) (Suliman et al, 2015).
Genetic Risk for PTSD – multiple new GWAS, (Misganaw PRS 2019, Neivergelt 2019, Gelernter 2019).
Laboratory findings – Single approx 25-min behavioural intervention (reminder + filler + mental rotation instructions for Tetris game play) 24 hours after trauma: tested after experimental trauma but not real-world trauma. Main outcome is reduction of intrusive memories over 1 week. Neither game play alone not trauma reminder cue alone was sufficinet: full intervention package is needed.
Computerized Visuospatial Tasks (Iyadurai et al, 2018; Horsh et al, 2017).
Appraisal/prep for future
Promote adaptive goal-directed coping